Ashley Bush is Professor of Neuroscience and Psychiatry at the University of Melbourne and the Director of the Melbourne Dementia Research Centre at The Florey Institute of Neuroscience & Mental Health. He is Co-Director of Biomarker Development for The Australian Imaging, Biomarkers and Lifestyle Study of Ageing (AIBL), and holds staff appointments in Psychiatry and Radiology at Massachusetts General Hospital, USA. He is the scientific founder of multiple biotechnology companies such as Cogstate Ltd and Collaborative Medicinal Development. He has over 440 publications, >40,000 citations, a h-index of 101, and 29 patents. Prof Bush is rated in the top 1% of neuroscience researchers worldwide for high impact citations (2014-2016, 2018), and classed as one of the World's Most Influential Scientific Minds by Clarivate Analytics.
1. Ayton, S., Wang, Y., Diouf, I., Schneider, J. A., Brockman, J., Morris, M. C., & Bush, A. I. (2019). Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology. Molecular Psychiatry, 45(Pt 1), 358. http://doi.org/10.1038/s41380-019-0375-7
2. Stockwell, B. R., Angeli, J. P. F., Bayir, H., Bush, A. I., Conrad, M., Dixon, S. J., et al. (2017). Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Cell, 171(2), 273–285. http://doi.org/10.1016/j.cell.2017.09.021
3. Ayton, S., Fazlollahi, A., Bourgeat, P., Raniga, P., Ng, A., Lim, Y. Y., et al. (2017). Cerebral quantitative susceptibility mapping predicts amyloid-β-related cognitive decline.Brain, 140(8), 2112–2119. http://doi.org/10.1093/brain/awx137
4. Ayton, S., Faux, N. G., Bush, A. I., & ADNI. (2015). Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE. Nature Communications, 6, 6760. http://doi.org/10.1038/ncomms7760
5. Ayton, S., Faux, N. G., & Bush, A. I. (2017). Association of Cerebrospinal Fluid Ferritin Level With Preclinical Cognitive Decline in APOE-ε4 Carriers. JAMA Neurology, 74(1), 122–125. http://doi.org/10.1001/jamaneurol.2016.4406
Light refreshments will be served after the seminar.
Host: Oskar Hansson